Endocrine Abstracts

Endometrial cancer (EC) is estrogen dependent and several enzymes control the local availability of these steroids by activating (i.e. aromatase, sulfatase, 17beta-hydroxysteroid dehydrogenase type 1 – HSD17B1) or deactivating estrogens (sulfotransferase, 17beta-hydroxysteroid dehydrogenase type 2 – HSD17B2). Imbalances in these enzymes are implied in EC development.In the present study, it is evaluated whether imbalances in these enzymes are a...